IMPLEMENTATION OF CRISPR/CAS9 GENOME EDITING TO GENERATE MURINE LUNG CANCER MODELS THAT DEPICT THE MUTATIONAL LANDSCAPE OF HUMAN DISEASE

Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease

Lung cancer is the most common cancer worldwide and the leading cause of cancer-related deaths in both men and women.Despite the development of novel therapeutic interventions, the 5-year survival rate for non-small cell lung cancer (NSCLC) patients remains low, demonstrating the necessity for novel treatments.One strategy to improve translational

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MODERN TECHNOLOGY OF PRODUCTION AND STRATEGY OF PROMOTION OF NEW CEREAL PRODUCTS ON UKRAINIAN CONSUMER MARKET

In the article, based on analysis of the ALPHA LIPOIC ACID 200MG market of dry breakfasts in Ukraine and calculations of the assortment of instant and quick-cooked cereals, which are implemented in trading networks of Odessa and Odessa region, it was established that studied supermarkets can not provide stable, complete and wide assortment of produ

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Tectonic geomorphology and volcano-tectonic interaction in the eastern boundary of the Southern Cascades (Hat Creek Graben region), California, USA

The eastern boundary of the Southern Cascades (Hat Creek Graben region), California, USA, is an extensively faulted volcanic corridor between the Cascade Range and Modoc Plateau.The east-west extending region is in the transition zone between the convergence and subduction of the Gorda Plate underneath the North American Plate; north-south shorteni

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Russet Sparrows spot alien chicks from their nests

Abstract Background In coevolutionary interactions between brood parasites and their hosts, host parents are under strong selection to evolve defenses against parasitism.Egg rejection is an efficient and common defense against parasitism, although some apparently suitable hosts do not reject cuckoo eggs.Methods Sparrows Ploceidae are widespread thr

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